In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

≥ 5 % of standard sample

Why all of a sudden is there so much interest in the safety of Titanium Dioxide?

Researchers from France and Luxembourg gave E171 (the much more food friendly name for Titanium Dioxide) in Europe and the United States, to lab rats in their drinking water for 100 days.

Of those rats, 40 per cent of the exposed rodents developed “preneoplastic lesions” or precancerous growths. The Titanium Dioxide also inhibited the immune systems of the rats and “accelerated” the growth of the lesions. France’s INRA agricultural research institute, which took part in the study, said in a statement.“These results demonstrate a role in initiating and promoting the early stages of colorectal cancer formation,” though it said no conclusion could be drawn about later phases of cancer, or of any danger to humans……….(not till they test it on us!!)

The results of the study were published in the Nature journal Scientific Reports.